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个人简介
职称:教授、博士生导师
E-mail: syshui207@126.com
个人履历
中国科学院海洋研究所博士毕业,2015年海南大学C类人才引进。主持国家自然科学基金、国家博士后科学基金、海南省重大项目、海南省自然基金及海南大学C类人才启动基金等10余项课题。以第一/通讯作者在Frontiers in Immunology、Fish & Shellfish Immunology、Aquaculture、Infection and Immunity、Vaccine等国际权威SCI刊物上发表论文30余篇,总影响因子达到80。
研究方向
着重于海洋鱼类免疫机制、海洋病原菌致病机理、疫苗研发及生物免疫制剂的研究。以基础研究为主,结合应用研究,积极推动水产养殖业的可持续发展。
项目课题
1. 基于创新型人才培养的水产微生物学实验课程改革与实践,海南省教育教学改革项目,2020.1-2022.12,项目主持。
2. 卵形鲳TLR3和TLR7亚家族鉴定及其信号通路在抗细菌感染中的作用机制,国家自然科学基金,2017.1-2020.12,项目主持。
3. 卵形鲳B淋巴细胞刺激因子的表达调控及其介导的免疫应答,国家自然科学基金,2018.1-2020.12,项目主持。
4. 海南海洋离岸大型网箱养殖产业园区关键技术集成示范应用,海南省重大项目,2016.1-2018.12,项目主持。
5. 美国红鱼酸性磷酸酶基因的表达调控及功能研究,海南省自然科学基金,2016.1-2017.12,项目主持。
学术奖励
入选“海南省领军人才”,获海南省“南海名家”青年项目、2019年度海南省科学技术二等奖、2019年度国家海洋科学技术二等奖、2016年度国家海洋科学技术二等奖、中国科学院优秀博士论文及中国科学院“院长特别奖”等多项奖项。
论文专著
1. Chen, X.J.1, Cao, Z.J.1, Zhang, Z.S., Wu, Y., Du, H.H., Sun, Y.*, Zhou, Y.C.*. B lymphocyte stimulating factor of Trachinotus ovatus (TroBLyS) promotes antibacterial immune defense. Aquaculture, 536, 2021, 736437. (通讯)
2. Zhou, Y.C.1, Chen, X.J.1, Cao, Z.J., Li, J.L., Long, H., Wu, Y., Zhang, Z.S., Sun, Y.* R848 is involved in the antibacterial immune response of golden pompano (Trachinotus ovatus) through TLR7/8-MyD88-NF-κB-signaling pathway. Frontiers in immunology, 11, 2020, 617522. (通讯)
3. Wu, Y.1, Zhou, Y.C.1, Cao, Z.J., Chen, X.J., Du, H.H., Sun, Y.* Interferon regulatory factor 7 contributes to the host response during Vibrio harveyi infection in the golden pompano Trachinotus ovatus. Developmental and Comparative Immunology, 117, 2021, 103959. (通讯)
4. Wang, L.1, Cao, Z.J.1, Liu, Y.X., Xiang, Y.J., Sun, Y.*, Zhou, Y.C. *, Wang, S.F., Guo, W.L. Establishment and characterization of a new cell line from the muscle of humpback grouper (Cromileptes altivelis). Fish Physiology and Biochemistry, 46, 2020, 1897-1907. (通讯)
5. Lei, Y., Qiu, R., Shen, Y., Zhou, Y.C., Cao, Z.J., Sun, Y.* Molecular characterization and antibacterial immunity functional analysis of liver-expressed antimicrobial peptide 2 (LEAP-2) gene in golden pompano (Trachinotus ovatus). Fish & Shellfish Immunology, 106, 2020, 833-843. (通讯)
6. Chen, Y.1, Zhou, Y.C.1, Yang, X.Y., Cao, Z.J., Chen, X.J., Qin, Q.W., Liu, C.S., Sun, Y.* Insulin-like growth factor binding protein 3 gene of golden pompano (TroIGFBP3) promotes antimicrobial immune defense. Fish & Shellfish Immunology, 103, 2020, 47-57. (通讯)
7. Sun, Y., Liu, H., Shen, Y., Huang, X., Song, F.G., Ge, X.L., Wang, A., Zhang, K.Z., Li, Y., Li C.Y., Wan, Y., * Li, J.L. Cas12a-Activated Universal Field-Deployable Detectors for Bacterial Diagnostics. ACS Omega, 5,2020, 14814-14821. (第一作者)
8. Wu, Y.1, Zhou, Y.1, Cao, Z.J., Sun, Y.*, Chen, Y., Xiang, Y.J, Wang, L., Zhang, S.N., Guo, W.L. Comparative analysis of the expression patterns of IL-1β, IL-11, and IL-34 in golden pompano (Trachinotus ovatus) following different pathogens challenge. Fish & Shellfish Immunology, 93, 2019, 863-870. (通讯)
9. Sun, B.M., Lei, Y., Cao, Z.J., Zhou, Y.C., Sun, Y.*, Wu, Y., Wang, S.F., Guo, W.L., Liu, C.S. TroCCL4, a CC chemokine of Trachinotus ovatus, is involved in the antimicrobial immune response. Fish & Shellfish Immunology, 86, 2019, 525-535. (通讯)
10. Cao, Z.J., Liu, X.C., Xiang, Y.J., Wang, L., Sun, Y.*, Zhou, Y.C.* Genetic polymorphism of MHC class IIα alleles and its association with resistance/susceptibility to viral nervous necrosis virus (VNNV) in golden pompano (Trachinotus ovatus). Aquaculture, 501, 2019, 144-152. (通讯)